How are trigger shots administered?
Trigger shots are given once per cycle before ovulation.
They can be injected either into the muscle (intramuscularly) or under the skin (subcutaneously).
They're most typically self-administered, and many women choose to do the shot under the skin on the abdomen.
Importance of trigger shots in IVF treatment
Trigger shots play a crucial role in IVF treatment.
The purpose of an ivf trigger shot timing is to send the eggs into a state of reproductive cell division called Meiosis (also known as maturation division) during the 36 hours preceding ovulation or retrieval.
The timing and efficiency of this process can determine the quality of eggs that are retrieved and used in embryo creation.
It also determines the outcome of the cycle.
When it comes to ovulation induction during the IVF treatment, we should choose and implement the trigger shot with utmost care.
It is one of the most important decisions a physician decides as the trigger shot highly affects the success rate of the IVF cycle.
Working of trigger shot for IVF treatment and Importance of its timing
In actuality, the trigger shot is human chorionic gonadotropin (hCG), a hormone that signals the follicles to rupture and release an egg.
In an ovarian stimulation cycle, gonadotropic hormones such as FSH and LH stimulate the ovaries for egg development to achieve pregnancy.
The trigger shot must be administered approximately 36 hours before IVF egg retrieval, as the timing is crucial for the success of the entire IVF process.
This trigger shot comprises of one of three medications:
1.
Urinary derived hCG (hCGu) shots.
2.
Recombinant hCG (hCGr) shots.
3.
Agonist trigger shots provoke a surge in the release of LH upon being injected into the human body.
Maturation or Meiosis of egg cells
The trigger shot in IVF treatment aims to send eggs into a reproductive division known as Meiosis.
During Meiosis, the objective is to decrease the number of eggs from 46 to 23 before egg retrieval or ovulation.
Trigger shots expel half of the chromosomes from the egg's nucleus in a membranous envelopment where they can get eroded on their own.
Different types of trigger shots
A trigger shot is often utilized for timed intercourse or SMEP.
Once the eggs reach the optimal development stage, a trigger shot prompts ovulation within 36-42 hours, i.
e.
, within five days.
After the trigger shot is administered, the couple is instructed to have intercourse daily or every other day for three days.
However, suppose a person is taking the shot as a part of your ovulation induction protocol.
In that case, the doctor will guide them on when and how to take it to synchronize it to other medications and procedures.
When a couple has already opted for an IVF treatment but still wants to proceed with the trigger shot, the eggs are extracted from the women's body within five days and then fertilized artificially in the lab.
Friday, February 25, 2022 at 4:12 PM